Atropine sulfate ophthalmic solution is a sterile, aqueous solution of atropine sulfate. The other ingredients are sodium chloride and water for injections. Atropine sulfate injection is reported to be physically incompatible with bromides, iodides, alkalis, noradrenaline bitartrate, metaraminol bitartrate and sodium bicarbonate. Read all of this leaflet carefully before you start using this medicine. Each singledose prefilled autoinjector provides a 1. Your doctor will be able to tell you about the specific condition for which you have been prescribed atropine injection. It is administered parenterally by subcutaneous, intramuscular or intravenous injection. Atropine sulfate injection, usp safety data sheet according to federal register vol. Jul 29, 2019 the 2 mg atropine autoinjector provides atropine base, 1. Mixture relevant identified uses of the substance or mixture and uses advised against intended use. Atropine injection may be used for the management of other conditions that are not mentioned above.
Each 1ml contains 300 micrograms in a sterile solution for injection. Atropine can dilate your pupils before examinations and can treat different eye problems. Looking for online definition of atropine sulfate in the medical dictionary. This injection contains the following inactive ingredients. The 2 mg atropine autoinjector is a singledose selfcontained unit designed for self or caregiver administration.
Atropine fda prescribing information, side effects and uses. Atropine sulfate is also used to block or reverse the adverse effects caused by some medicines and certain type of pesticides. Atropine sulfate ophthalmic ointment funnel into a 50ml beaker, and evaporate to neardryness under a stream of nitrogen. Stability of milrinone and epinephrine, atropine sulfate. Find out what health conditions may be a health risk when taken with atropine injection.
It is typically given intravenously or by injection into a muscle. Atropine injection is given before anaesthesia to decrease mucus secretions, such as saliva. Atropine injection bp atropine sulfate information myvmc. If you have any concerns about taking this medicine, ask your doctor or pharmacist. A haze or precipitate may form within 15 minutes when atropine sulfate is mixed with methohexital sodium solutions. Atropine sulfate atropine sulfate injection international. Definition chromatographic system atropine sulfate ophthalmic ointment is atropine sulfate see chromatography.
It may contain suitable stabilizers and antimicrobial agents. Atropine is a white crystalline alkaloid which may be extracted from belladonna root and hyoscyamine or may be produced synthetically. Atropine sulfate injection, usp is a sterile, nonpyrogenic, isotonic, clear solution of atropine sulfate in water for injection with sodium chloride sufficient to render the solution isotonic. Read all of this leaflet carefully before you start using this medicine because it. Atropine sulfate injection, for intravenous, intramuscular, subcuatenous or endotracheal use. May cause eye, skin, or respiratory system irritation. Atropine sulfate injection sa vetone atropine inhibits the muscarinic actions of acetylcholine on structures innervated by postganglionic cholinergic nerves, and on smooth muscles which respond to endogenous acetylcholine but are not so innervated. Duplicate solutions of admixtures of milrinone injection 1 mgml and epinephrine injection 1. Atropine sulfate injection usp is commonly classified as an anticholinergic or antiparasympathetic. Caution patients that atropine impairs heat regulation.
Atropine sulfate 1mg in 1ml solution for injection atropine sulphate referred to as atropine solution for injection in this leaflet d0325300000 read all of this leaflet carefully before you start using this medicine because it contains important information for you. If a person vomits place them in the recovery position so that vomit will not reenter the mouth and throat. Microsoft word atropine sulfate injection sds final 01092019 author. In refractory cases subconjunctival atropine can be administered as an epibulbar injection. Westward pharmaceuticals atropine sulfate for injection 0.
The injection is supplied as a single 10ml prefilled syringe in a carton. Material may be irritating to the mucous membranes and upper respiratory tract. Atropine while the qas has attempted to contact all owners, this has not always been possible. Atropine sulfate atropine sulfate injection, solution medpharmex, inc. Atropine functions as a sympathetic, competitive antagonist of muscarinic cholinergic receptors, thereby abolishing the effects of parasympathetic stimulation. Atropine sulfate injection, usp, is a sterile aqueous solution of atropine sulfate. Jan 19, 2018 atropine sulfate injection usp is a sterile, nonpyrogenic solution of atropine sulfate monohydrate in water for injection with sodium chloride sufficient to render the solution isotonic. Atropine sulfate injection usp is a sterile, nonpyrogenic solution of atropine sulfate monohydrate in water for injection with sodium chloride sufficient to render the solution isotonic. Oct 24, 2018 the bioavailability of atropine sulfate ophthalmic solution, usp 1% was assessed in six healthy subjects, 24 to 29 years of age. The invention belongs to the technical field of biological medicines, discloses an atropine sulfate injection and a production process thereof and mainly solves the problems of poor heat stability, large quantity of drop points in a sterilization process, low raw material utilization rate and the like. The qas would welcome notification from any holder who has been omitted or incorrectly acknowledged. In these cases it is important to increase antiinflammatory therapy by using subconjunctival depot cortisone injections with the epibulbar atropine injection. Atropine sulfate injection, for intravenous, intramuscular, subcutaneous, intraosseous or endotracheal use. Atropine sulfate injection bp product information name.
Atropine sulfate injection 1mg in 1ml patient information. Atropine sulfate 400 micrograms in 1ml solution for injection atropine sulphate referred to as atropine solution for injection in this leaflet what is in this leaflet 1. Atropine sulfate injection bp against the benefits they expect it will have for you. For further information about unapproved drugs, click here. Atropine sulfate injection, usp is a sterile solution of atropine sulfate in water for injection.
Atropine sulfate injection bp product information name of. The 2 mg atropine autoinjector provides atropine base, 1. What atropine solution for injection is and what it is used for 2. Eye drops are also available which are used to treat uveitis and early amblyopia. Atropine sulfate injection is a solution containing atropine sulfate, an anticholinergic drug that blocks the effects of acetylcholine in the body resulting is effects on many organ systems including the eyes, gastrointestinal tract, heart, lung and central nervous. Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate and to decrease saliva production during surgery. May 11, 2015 atropine sulfate injection is reported to be physically incompatible with bromides, iodides, alkalis, noradrenaline bitartrate, metaraminol bitartrate and sodium bicarbonate. Information for the user atropine sulfate 600 micrograms in 1ml solution for injection atropine sulfate referred to as. The bioavailability of atropine sulfate ophthalmic solution, usp 1% was assessed in six healthy subjects, 24 to 29 years of age. Atropine sulfate injection bp product information 2 11 glands and smooth and cardiac muscle. Atropine sulfate is the sulfate salt of atropine, a naturallyoccurring alkaloid isolated from the plant atropa belladonna.
The total amount of atropine used for carbamate poisoning is usually less than with organophosphate insecticide or nerve agent poisoning. Strenuous activity in a hot strenuous activity in a hot environment may cause heat stroke. Atropine sulfate injection bp product information name of the. Patient information for atropine sulphate injection bp 600mcgml including dosage instructions and possible side effects. This agent may induce tachycardia, inhibit secretions, and. Atropine sulfate injection, usp vial emergency medical products.
Atropine sulfate injection, usp is a sterile, isotonic solution of atropine sulfate in water for injection q. Webmd provides common contraindications for atropine injection. Atropine sulfate monohydrate belongs to a group of medicines called antimuscarinic agents. In severe intoxication, physostigmine salicylate may be administered atropine sulfate ophthalmic solution, 1% preparation date. Sigmaaldrich offers a number of atropine sulfate products. Atropine sulfate injection 600mcg in 1ml hameln summary. What atropine solution for injection looks like and contents of the pack. Atropine sulfate injection is used as a preanesthetic adjuvant or to reduce salivation, bronchial secretion or internal peristalis associated with colic or diarrhea. What you need to know before you are given atropine solution for injection 3. Ophthalmic productsquality tests particulate and foreign. Atropine sulfate definition of atropine sulfate by medical.
It may also include sodium hydroxide and sulfuric acid. Healthfirst is your onestop solution for dental practice emergency preparedness, infection control, dental waste, and compliance. Atropine sulfate ophthalmic solution, 1% msdsdigital. Atropine sulfate injection in therapeutic doses counteracts the peripheral dilatation and abrupt decrease in blood pressure produced by choline esters. Cn104555869a atropine sulfate injection and production. What atropine sulfate injection bp is for atropine sulfate injection bp is most commonly used to reduce body secretions such as.
This drug has not been found by fda to be safe and effective, and this labeling has not been approved by fda. Responses to postganglionic cholinergic nerve solution also may be inhibited by atropine but this occurs less readily than with responses to injected exogenous choline esters. Dec 04, 2019 atropine sulfate injection, usp is a sterile, nonpyrogenic isotonic solution of atropine sulfate monohydrate in water for injection with sodium chloride sufficient to render the solution isotonic. Severely poisoned patients may exhibit significant tolerance to atropine. In these cases it is important to increase antiinflammatory therapy by using subconjunctival depot cortisone injections with the. This injection contains the active ingredient atropine sulphate. Pharmaceutical product used as anticholinergic agent details of the supplier of the safety data sheet 2. Atropine sulfate injection, usp is a sterile, nonpyrogenic isotonic solution of atropine sulfate monohydrate in water for injection with sodium chloride sufficient to render the solution isotonic. Atropine disappears rapidly from the blood following injection and is distributed throughout the.
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